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Cardinals vs Chargers matchup
The gist
The Chargers host the Cardinals in Week 1 on Sept. 13 at SoFi Stadium.
Most pickers expect a Chargers win; the spread's size is the open question.
How it unfolded
- Aug 28, 2026The Chargers announce the Week 1 home game against the Cardinals at SoFi Stadium, Sunday, September 13, kickoff 1:25 p.m. PT on CBS.
- Sep 8, 2026BetMGM publishes its Cardinals vs. Chargers Week 1 prediction, odds and best prop bets.
- Sep 9, 2026azcentral reports the Chargers are 10.5-point favorites, -550 on the moneyline, with Arizona at +425, per BetMGM Sportsbook.