Bones may release proteins that slow aging
The gist
Gently squeezing mice's leg bones extended their lives by nearly 3 months, about nine human years.
The work suggests bone-released proteins like PEDF may drive antiaging effects, in mice only.
How it unfolded
- Oct 30, 2026Science.org reports that mechanical strain on the skeleton triggers osteocytes to secrete antiaging chemicals, and that gently squeezing mice's leg bones extended their lives by nearly 3 months.
- Nov 2, 2026Science.org's Bluesky account posts that bones may release proteins that slow aging and extend life span, and that exercise triggers osteocytes to secrete antiaging chemicals in mice.
- Nov 2, 2026A Hacker News post titled "Bones may release proteins that slow aging and extend life span (science.org)" gets 7 points.